Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Continuous Crystallization of Proteins in a Tubular Plug-Flow Crystallizer

Protein crystals have many important applications in many fields, including pharmaceutics. Being more stable than other formulations, and having a high degree of purity and bioavailability, they are especially promising in the area of drug delivery. In this contribution, the development of a continuously operated tubular crystallizer for the production of protein crystals has been described. Us...

متن کامل

Selective Crystallization of Metastable α-Form of L- glutamic Acid through Feedback Concentration Control

Polymorphism is described as the ability of a compound to adopt different crystalline arrangements. Although chemically identical, different polymorphic structures display a variation in its physical properties such as crystal morphology, density, solubility, and color. These in turn exert an influence on the performance of the product; for example, the bioavailability and shelf-life of pharmac...

متن کامل

l-Glutamic acid hydro­chloride at 153 K

THE TITLE COMPOUND [SYSTEMATIC NAME: (S)-1,3-dicarboxy-propanaminium chloride], C(5)H(10)NO(4) (+)·Cl(-), has been investigated previously by Dawson [Acta Cryst. (1953). 6, 81-83], with R = 0.106 and without the location of H atoms, and then by Sequeira, Rajagopal & Chidambaram [Acta Cryst. (1972). B28, 2514-2519] using neutron diffraction with R = 0.043. The present determination at 153 K has ...

متن کامل

Continuous Plug Flow Crystallization of Pharmaceutical Compounds

Crystallization processes in the pharmaceutical industry are usually designed to obtain crystals with controlled size, shape, purity, and polymorphic form. Knowledge of the process conditions required to fabricate crystals with controlled characteristics is critical during process development. In this work, continuous crystallization of Ketoconazole, Flufenamic Acid, and L-Glutamic Acid in a no...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Organic Process Research & Development

سال: 2015

ISSN: 1083-6160,1520-586X

DOI: 10.1021/acs.oprd.5b00206